Rubella virus and novel concepts for congenital rubella embryopathy
As a biologist working in the field of virology my research focus is set on the interaction of rubella virus with its respective host cell. This efficient viral teratogen is a strictly human-specific viral pathogen. The cellular mechanisms leading to the impairment of human development are still unknown. Through my research I want to add new data to our current understanding of these mechanisms. This requires the evaluation of rubella virus-specific effects on suitable ex-vivo cell culture systems such as undifferentiated and differentiated induced pluripotent stem cells (iPSCs).
During my study of Biological Sciences at the University of Halle-Wittenberg a lecture on viruses as pirates of a cell initiated my interest in virology. From 1999 to 2000 I was enroled at the Queen’s University of Belfast as a non-graduating student. There I attended classes in general and specialiced virology. In 2006, during my doctoral thesis, I worked as a research scholar in the laboratory of Prof. Teryl Frey at Georgia State University in Atlanta. Hereafter more recent points of the timeline of my research work are summarized.