Publications

2023
Schulz J, Schilling E, Fabian C, Zenclussen AC, Stojanovska V, Claus C. Dissecting Rubella Placental Infection in an In Vitro Trophoblast Model. International Journal of Molecular Sciences. 2023; 24(9):7894. doi.org/10.3390/ijms24097894

Henschke V, Hild K, Schilling E, Haas J, Filipova V, Erbe S, König R, Hübschen JM, Laufs U, Claus C, Boeckel JN. Rubella virus infection in endothelial cells reduces angiogenesis via interferon beta-induced CXCL10. iScience. 2023;26(4):106352. doi: 10.1016/j.isci.2023.106352.

Jung M, Hartmann C, Ehrhardt T, Peter LM, Abid CL, Harwardt B, Hirschfeld J, Claus C, Haferkamp U, Pless O, Nastainczyk-Wulf M, Kehlen A, Schlote D, Schroder IS, Rujescu D. Generation of a set of induced pluripotent stem cell lines from two Alzheimer disease patients carrying APOE4 (MLUi007-J; MLUi008-A) and healthy old donors carrying APOE3 (MLUi009-A; MLUi010-B) to study APOE in aging and disease. Stem Cell Res. 2023;69:103072. doi: 10.1016/j.scr.2023.103072.

2022
Wald ME, Claus C, Konrath A, Nieper H, Muluneh A, Schmidt V, Vahlenkamp TW, Sieg M. Ivermectin Inhibits the Replication of Usutu Virus In Vitro. Viruses. 2022;14(8):1641. doi: 10.3390/v14081641.

Hufsky F, Abecasis A, Agudelo-Romero P, Bletsa M, Brown K, Claus C, Deinhardt-Emmer S, Deng L, Friedel CC, Gismondi MI, Kostaki EG, Kühnert D, Kulkarni-Kale U, Metzner KJ, Meyer IM, Miozzi L, Nishimura L, Paraskevopoulou S, Pérez-Cataluña A, Rahlff J, Thomson E, Tumescheit C, van der Hoek L, Van Espen L, Vandamme AM, Zaheri M, Zuckerman N, Marz M. Women in the European Virus Bioinformatics Center. Viruses. 2022;14(7):1522. doi: 10.3390/v14071522.

Schilling E, Wald ME, Schulz J, Werner LE, Claus C. Interferon Signaling- Dependent Contribution of Glycolysis to Rubella Virus Infection. Pathogens. 2022 ;11(5):537. doi: 10.3390/pathogens11050537.

Maria Elisabeth Wald, Michael Sieg, Erik Schilling, Marco Binder, Thomas Wilhelm Vahlenkamp, Claudia Claus The Interferon Response Dampens the Usutu Virus Infection-Associated Increase in Glycolysis Front. Cell. Infect. Microbiol., 04 February 2022; https://doi.org/10.3389/fcimb.2022.823181 

Erik Schilling, Lukas Pfeiffer, Sunna Hauschildt, Ulrike Koehl, Claudia Claus, CD14 Is Involved in the Interferon Response of Human Macrophages to Rubella Virus Infection. Biomedicines 2022, 10(2), 266; https://doi.org/10.3390/biomedicines10020266

2021
Claus C*, Fritz R*, Schilling E, Reibetanz U, The Metabolic Response of Various Cell Lines to Microtubule-Driven Uptake of Lipid- and Polymer-Coated Layer-by-Layer Microcarriers. Pharmaceutics 2021, 13, 1441. https://doi.org/10.3390/pharmaceutics13091441 

Böhnke J, Pinkert S, Schmidt M, Binder H, Bilz NC, Jung M, Reibetanz U, Beling A, Rujescu D, Claus C. Coxsackievirus B3 Infection of Human iPSC Lines and Derived Primary Germ-Layer Cells Regarding Receptor Expression. Int J Mol Sci. 2021 Jan 27;22(3):1220. doi: 10.3390/ijms22031220

2020
Claus C, Jung M, Hübschen JM. Pluripotent stem cell-based models: a peephole into virus infections during early pregnancy. Cells. 2020, 9, 542. doi: 10.3390/cells9030542

Scheffler K, Bilz NC, Brueckner M, Stanifer ML, Boulant S, Claus C, Reibetanz U. Enhanced uptake and endosomal release of LbL microcarriers functionalized with reversible fusion proteins. ACS Appl. Bio Mater. 2020, 3, 3, 1553-1567 doi: 10.1021/acsabm.9b01168

2019
Bilz NC, Willscher E, Binder H, Böhnke J, Stanifer ML, Hübner D, Boulant S, Liebert UG, Claus C. Teratogenic Rubella Virus Alters the Endodermal Differentiation Capacity of Human Induced Pluripotent Stem Cells. Cells. 2019; 8(8). doi: 10.3390/cells8080870.

2018
Zobel S, Lorenz M, Frascaroli G, Böhnke J, Bilz NC, Stanifer ML, Boulant S, Bergs S, Liebert UG, Claus C. Rubella Virus Strain-Associated Differences in the Induction of Oxidative Stress Are Independent of Their Interferon Activation. Viruses. 2018;10(10). pii: E540. doi: 10.3390/v10100540.

Kräter M, Sapudom J, Bilz NC, Pompe T, Guck J, Claus C. Alterations in Cell Mechanics by Actin Cytoskeletal Changes Correlate with Strain-Specific Rubella Virus Phenotypes for Cell Migration and Induction of Apoptosis. Cells. 2018;7(9). pii: E136. doi: 10.3390/cells7090136.

Scheffler K, Claus C, Stanifer ML, Boulant S, Reibetanz U. Reversible Fusion Proteins as a Tool to Enhance Uptake of Virus-Functionalized LbL Microcarriers. Biomacromolecules. 2018;19(8):3212-3223. doi: 10.1021/acs.biomac.8b00360.

Bilz NC, Jahn K, Lorenz M, Lüdtke A, Hübschen JM, Geyer H, Mankertz A, Hübner D, Liebert UG, Claus C. Rubella Viruses Shift Cellular Bioenergetics to a More Oxidative and Glycolytic Phenotype with a Strain-Specific Requirement for Glutamine. J Virol. 2018;92(17). pii: e00934-18. doi: 10.1128/JVI.00934-18.

2017
Hübner D, Jahn K, Pinkert S, Böhnke J, Jung M, Fechner H, Rujescu D, Liebert UG, Claus C. Infection of iPSC Lines with Miscarriage-Associated Coxsackievirus and Measles Virus and Teratogenic Rubella Virus as a Model for Viral Impairment of Early Human Embryogenesis. ACS Infect Dis. 2017 ;3(12):886-897. doi: 10.1021/acsinfecdis.7b00103.

Claus C, Bergs S, Emmrich NC, Hübschen JM, Mankertz A, Liebert UG. A Sensitive One-Step TaqMan Amplification Approach for Detection of Rubella Virus Clade I and II Genotypes in Clinical Samples. Arch Virol. 2017; 162(2):477-486. doi:10.1007/s00705-016-3131-1.


2016
Reibetanz U, Hübner D, Jung M, Liebert UG, Claus C. Influence of Growth Characteristics of Induced Pluripotent Stem Cells on Their Uptake Efficiency for Layer-by-Layer Microcarriers. ACS Nano. 2016;10(7):6563-73. doi: 10.1021/acsnano.6b00999.

Geyer H, Bauer M, Neumann J, Lüdde A, Rennert P, Friedrich N, Claus C, Perelygina L, Mankertz A. Gene expression profiling of rubella virus infected primary endothelial cells of fetal and adult origin. Virol J. 2016;13:21. doi: 10.1186/s12985-016-0475-9.

2015
Claus C, Manssen L, Hübner D, Roßmark S, Bothe V, Petzold A, Große C, Reins M, Mankertz A, Frey TK, Liebert UG. Activation of the Mitochondrial Apoptotic Signaling Platform during Rubella Virus Infection. Viruses. 2015; 7(12):6108-26. doi: 10.3390/v7122928.

Fichtner M, Claus C, Lessig-Owlanj J, Arnhold J, Reibetanz U. The Application of LbL-Microcarriers for the Treatment of Chronic Inflammation: Monitoring the Impact of LbL-Microcarriers on Cell Viability. Macromol Biosci. 2015; 15(4):546-57. doi: 10.1002/mabi.201400405.

2014
Milbradt J, Kraut A, Hutterer C, Sonntag E, Schmeiser C, Ferro M, Wagner S, Lenac T, Claus C, Pinkert S, Hamilton ST, Rawlinson WD, Sticht H, Couté Y, Marschall M. Proteomic Analysis of the Multimeric Nuclear Egress Complex of Human Cytomegalovirus. Mol Cell Proteomics. 2014; 13(8):2132-46. doi: 10.1074/mcp.M113.035782.

Claus C, Liebert UG. A Renewed Focus on the Interplay Between Viruses and Mitochondrial Metabolism. Arch Virol. 2014; 159(6):1267-77. doi:10.1007/s00705-013-1841-1.

2013
Claus C, Schönefeld K, Hübner D, Chey S, Reibetanz U, Liebert UG. Activity Increase in Respiratory Chain Complexes by Rubella Virus with Marginal Induction of Oxidative Stress. J Virol. 2013; 87(15):8481-92. doi: 10.1128/JVI.00533-13.

2012
Claus C, Tzeng WP, Liebert UG, Frey TK. Rubella Virus-Like Replicon Particles: Analysis of Encapsidation Determinants and Non-Structural Roles of Capsid Protein in Early Post-Entry Replication. J Gen Virol. 2012; 93(Pt3):516-25. doi: 10.1099/vir.0.038984-0.

2011
Claus C, Chey S, Heinrich S, Reins M, Richardt B, Pinkert S, Fechner H, Gaunitz F, Schäfer I, Seibel P, Liebert UG. Involvement of p32 and Microtubules in Alteration of Mitochondrial Functions by Rubella Virus. J Virol. 2011; 85(8):3881-92. doi: 10.1128/JVI.02492-10.

Chey S, Claus C, Liebert UG. Improved Method for Simultaneous Isolation of Proteins and Nucleic Acids. Anal Biochem. 2011; 411(1):164-6. doi: 10.1016/j.ab.2010.11.020.

2010

2007
Claus C, Tzeng WP, Liebert UG, Frey TK. Rubella Virus-Induced Superinfection Exclusion Studied in Cells with Persisting Replicons. J Gen Virol. 2007; 88(Pt10):2769-73.

Claus C, Tzeng WP, Liebert UG, Frey TK. Analysis of the Selective Advantage Conferred by a C-E1 Fusion Protein Synthesized by Rubella Virus DI RNAs. Virology. 2007; 369(1):19-34.

2006
Claus C, Hofmann J, Uberla K, Liebert UG. Rubella Virus Pseudotypes and a Cell-Cell Fusion Assay as Tools for Functional Analysis of the Rubella Virus E2 and E1 Envelope Glycoproteins. J Gen Virol. 2006; 87(Pt 10):3029-37.

Reibetanz U, Claus C, Typlt E, Hofmann J, Donath E. Defoliation and Plasmid Delivery with Layer-by-Layer Coated Colloids. Macromol Biosci. 2006; 6(2):153-60.

2023
Schulz J, Schilling E, Fabian C, Zenclussen AC, Stojanovska V, Claus C. Dissecting Rubella Placental Infection in an In Vitro Trophoblast Model. International Journal of Molecular Sciences. 2023; 24(9):7894. doi.org/10.3390/ijms24097894

Henschke V, Hild K, Schilling E, Haas J, Filipova V, Erbe S, König R, Hübschen JM, Laufs U, Claus C, Boeckel JN. Rubella virus infection in endothelial cells reduces angiogenesis via interferon beta-induced CXCL10. iScience. 2023;26(4):106352. doi: 10.1016/j.isci.2023.106352.

Jung M, Hartmann C, Ehrhardt T, Peter LM, Abid CL, Harwardt B, Hirschfeld J, Claus C, Haferkamp U, Pless O, Nastainczyk-Wulf M, Kehlen A, Schlote D, Schroder IS, Rujescu D. Generation of a set of induced pluripotent stem cell lines from two Alzheimer disease patients carrying APOE4 (MLUi007-J; MLUi008-A) and healthy old donors carrying APOE3 (MLUi009-A; MLUi010-B) to study APOE in aging and disease. Stem Cell Res. 2023;69:103072. doi: 10.1016/j.scr.2023.103072.

2022
Wald ME, Claus C, Konrath A, Nieper H, Muluneh A, Schmidt V, Vahlenkamp TW, Sieg M. Ivermectin Inhibits the Replication of Usutu Virus In Vitro. Viruses. 2022;14(8):1641. doi: 10.3390/v14081641.

Hufsky F, Abecasis A, Agudelo-Romero P, Bletsa M, Brown K, Claus C, Deinhardt-Emmer S, Deng L, Friedel CC, Gismondi MI, Kostaki EG, Kühnert D, Kulkarni-Kale U, Metzner KJ, Meyer IM, Miozzi L, Nishimura L, Paraskevopoulou S, Pérez-Cataluña A, Rahlff J, Thomson E, Tumescheit C, van der Hoek L, Van Espen L, Vandamme AM, Zaheri M, Zuckerman N, Marz M. Women in the European Virus Bioinformatics Center. Viruses. 2022;14(7):1522. doi: 10.3390/v14071522.

Schilling E, Wald ME, Schulz J, Werner LE, Claus C. Interferon Signaling- Dependent Contribution of Glycolysis to Rubella Virus Infection. Pathogens. 2022 ;11(5):537. doi: 10.3390/pathogens11050537.

Maria Elisabeth Wald, Michael Sieg, Erik Schilling, Marco Binder, Thomas Wilhelm Vahlenkamp, Claudia Claus The Interferon Response Dampens the Usutu Virus Infection-Associated Increase in Glycolysis Front. Cell. Infect. Microbiol., 04 February 2022; https://doi.org/10.3389/fcimb.2022.823181 

Erik Schilling, Lukas Pfeiffer, Sunna Hauschildt, Ulrike Koehl, Claudia Claus, CD14 Is Involved in the Interferon Response of Human Macrophages to Rubella Virus Infection. Biomedicines 2022, 10(2), 266; https://doi.org/10.3390/biomedicines10020266

2021
Claus C*, Fritz R*, Schilling E, Reibetanz U, The Metabolic Response of Various Cell Lines to Microtubule-Driven Uptake of Lipid- and Polymer-Coated Layer-by-Layer Microcarriers. Pharmaceutics 2021, 13, 1441. https://doi.org/10.3390/pharmaceutics13091441 

Böhnke J, Pinkert S, Schmidt M, Binder H, Bilz NC, Jung M, Reibetanz U, Beling A, Rujescu D, Claus C. Coxsackievirus B3 Infection of Human iPSC Lines and Derived Primary Germ-Layer Cells Regarding Receptor Expression. Int J Mol Sci. 2021 Jan 27;22(3):1220. doi: 10.3390/ijms22031220

2021
Claus C*, Fritz R*, Schilling E, Reibetanz U, The Metabolic Response of Various Cell Lines to Microtubule-Driven Uptake of Lipid- and Polymer-Coated Layer-by-Layer Microcarriers. Pharmaceutics 2021, 13, 1441. https://doi.org/10.3390/pharmaceutics13091441 

Böhnke J, Pinkert S, Schmidt M, Binder H, Bilz NC, Jung M, Reibetanz U, Beling A, Rujescu D, Claus C. Coxsackievirus B3 Infection of Human iPSC Lines and Derived Primary Germ-Layer Cells Regarding Receptor Expression. Int J Mol Sci. 2021 Jan 27;22(3):1220. doi: 10.3390/ijms22031220

2020
Claus C, Jung M, Hübschen JM. Pluripotent stem cell-based models: a peephole into virus infections during early pregnancy. Cells. 2020, 9, 542. doi: 10.3390/cells9030542

Scheffler K, Bilz NC, Brueckner M, Stanifer ML, Boulant S, Claus C, Reibetanz U. Enhanced uptake and endosomal release of LbL microcarriers functionalized with reversible fusion proteins. ACS Appl. Bio Mater. 2020, 3, 3, 1553-1567. doi: 10.1021/acsabm.9b01168

2019
Bilz NC, Willscher E, Binder H, Böhnke J, Stanifer ML, Hübner D, Boulant S, Liebert UG, Claus C. Teratogenic Rubella Virus Alters the Endodermal Differentiation Capacity of Human Induced Pluripotent Stem Cells. Cells. 2019; 8(8). doi: 10.3390/cells8080870.

2018
Zobel S, Lorenz M, Frascaroli G, Böhnke J, Bilz NC, Stanifer ML, Boulant S, Bergs S, Liebert UG, Claus C. Rubella Virus Strain-Associated Differences in the Induction of Oxidative Stress Are Independent of Their Interferon Activation. Viruses. 2018;10(10). pii: E540. doi: 10.3390/v10100540.

Kräter M, Sapudom J, Bilz NC, Pompe T, Guck J, Claus C. Alterations in Cell Mechanics by Actin Cytoskeletal Changes Correlate with Strain-Specific Rubella Virus Phenotypes for Cell Migration and Induction of Apoptosis. Cells. 2018;7(9). pii: E136. doi: 10.3390/cells7090136.

Scheffler K, Claus C, Stanifer ML, Boulant S, Reibetanz U. Reversible Fusion Proteins as a Tool to Enhance Uptake of Virus-Functionalized LbL Microcarriers. Biomacromolecules. 2018;19(8):3212-3223. doi: 10.1021/acs.biomac.8b00360.

Bilz NC, Jahn K, Lorenz M, Lüdtke A, Hübschen JM, Geyer H, Mankertz A, Hübner D, Liebert UG, Claus C. Rubella Viruses Shift Cellular Bioenergetics to a More Oxidative and Glycolytic Phenotype with a Strain-Specific Requirement for Glutamine. J Virol. 2018;92(17). pii: e00934-18. doi: 10.1128/JVI.00934-18.

2017
Hübner D, Jahn K, Pinkert S, Böhnke J, Jung M, Fechner H, Rujescu D, Liebert UG, Claus C. Infection of iPSC Lines with Miscarriage-Associated Coxsackievirus and Measles Virus and Teratogenic Rubella Virus as a Model for Viral Impairment of Early Human Embryogenesis. ACS Infect Dis. 2017;3(12):886-897. doi: 10.1021/acsinfecdis.7b00103.

Claus C, Bergs S, Emmrich NC, Hübschen JM, Mankertz A, Liebert UG. A Sensitive One-Step TaqMan Amplification Approach for Detection of Rubella Virus Clade I and II Genotypes in Clinical Samples. Arch Virol. 2017; 162(2):477-486. doi:10.1007/s00705-016-3131-1.


2016
Reibetanz U, Hübner D, Jung M, Liebert UG, Claus C. Influence of Growth Characteristics of Induced Pluripotent Stem Cells on Their Uptake Efficiency for Layer-by-Layer Microcarriers. ACS Nano. 2016;10(7):6563-73. doi: 10.1021/acsnano.6b00999.

Geyer H, Bauer M, Neumann J, Lüdde A, Rennert P, Friedrich N, Claus C, Perelygina L, Mankertz A. Gene expression profiling of rubella virus infected primary endothelial cells of fetal and adult origin. Virol J. 2016;13:21. doi: 10.1186/s12985-016-0475-9.

2015
Claus C, Manssen L, Hübner D, Roßmark S, Bothe V, Petzold A, Große C, Reins M, Mankertz A, Frey TK, Liebert UG. Activation of the Mitochondrial Apoptotic Signaling Platform during Rubella Virus Infection. Viruses. 2015; 7(12):6108-26. doi: 10.3390/v7122928.

Fichtner M, Claus C, Lessig-Owlanj J, Arnhold J, Reibetanz U. The Application of LbL-Microcarriers for the Treatment of Chronic Inflammation: Monitoring the Impact of LbL-Microcarriers on Cell Viability. Macromol Biosci. 2015; 15(4):546-57. doi: 10.1002/mabi.201400405.

2014
Milbradt J, Kraut A, Hutterer C, Sonntag E, Schmeiser C, Ferro M, Wagner S, Lenac T, Claus C, Pinkert S, Hamilton ST, Rawlinson WD, Sticht H, Couté Y, Marschall M. Proteomic Analysis of the Multimeric Nuclear Egress Complex of Human Cytomegalovirus. Mol Cell Proteomics. 2014; 13(8):2132-46. doi: 10.1074/mcp.M113.035782.

Claus C, Liebert UG. A Renewed Focus on the Interplay Between Viruses and Mitochondrial Metabolism. Arch Virol. 2014; 159(6):1267-77. doi:10.1007/s00705-013-1841-1.

2013
Claus C, Schönefeld K, Hübner D, Chey S, Reibetanz U, Liebert UG. Activity Increase in Respiratory Chain Complexes by Rubella Virus with Marginal Induction of Oxidative Stress. J Virol. 2013; 87(15):8481-92. doi: 10.1128/JVI.00533-13.

2012
Claus C, Tzeng WP, Liebert UG, Frey TK. Rubella Virus-Like Replicon Particles: Analysis of Encapsidation Determinants and Non-Structural Roles of Capsid Protein in Early Post-Entry Replication. J Gen Virol. 2012; 93(Pt3):516-25. doi: 10.1099/vir.0.038984-0.

2011
Claus C, Chey S, Heinrich S, Reins M, Richardt B, Pinkert S, Fechner H, Gaunitz F, Schäfer I, Seibel P, Liebert UG. Involvement of p32 and Microtubules in Alteration of Mitochondrial Functions by Rubella Virus. J Virol. 2011; 85(8):3881-92. doi: 10.1128/JVI.02492-10.

Chey S, Claus C, Liebert UG. Improved Method for Simultaneous Isolation of Proteins and Nucleic Acids. Anal Biochem. 2011; 411(1):164-6. doi: 10.1016/j.ab.2010.11.020.

2010

2007
Claus C, Tzeng WP, Liebert UG, Frey TK. Rubella Virus-Induced Superinfection Exclusion Studied in Cells with Persisting Replicons. J Gen Virol. 2007; 88(Pt10):2769-73.

Claus C, Tzeng WP, Liebert UG, Frey TK. Analysis of the Selective Advantage Conferred by a C-E1 Fusion Protein Synthesized by Rubella Virus DI RNAs. Virology. 2007; 369(1):19-34.

2006
Claus C, Hofmann J, Uberla K, Liebert UG. Rubella Virus Pseudotypes and a Cell-Cell Fusion Assay as Tools for Functional Analysis of the Rubella Virus E2 and E1 Envelope Glycoproteins. J Gen Virol. 2006; 87(Pt 10):3029-37.

Reibetanz U, Claus C, Typlt E, Hofmann J, Donath E. Defoliation and Plasmid Delivery with Layer-by-Layer Coated Colloids. Macromol Biosci. 2006; 6(2):153-60.